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Folate, or folic acid, is often high on the list for consumers in the search for natural supplements for overall wellness - for good reason. This B-vitamin, plays essential roles in DNA synthesis, brain health, supporting cognitive function and supporting healthy heart function, so maintaining levels in the body is important for everyone! However, not all forms of folate are created equal and understanding their differences is a crucial step when selecting multivitamins for a healthy lifestyle.
FOLIC ACID AND MTHFR: THE PROBLEMS!
Folic acid is a synthetic form of vitamin B that requires multiple steps to become biologically active. This means our bodies need to work hard to create the key enzymes, dihydrofolate reductase (DHFR) and methylenetetrahydrofolate reductase (MTHFR), to make full use of this important nutrient. Many of us carry what are known as genetic polymorphisms, or variations, that reduce the activity of MTHFR.This limits our ability to convert folic acid into its active form, and results in unmetabolised folic acid accumulating in the bloodstream. A multivitamin should take these limitations into account, especially in formulations for those aged over , where nutrient absorption and metabolic efficiency naturally decline.
HOW QUATREFOLIC® IS DIFFERENT
Quatrefolic® is a biologically active form of folate used directly by the body, with no need to be broken down by enzymatic processes like folic acid. In fact, the DHFR and MTHFR conversion steps are entirely bypassed, making it a form of vitamin B that’s immediately available at the cellular level. Quatrefolic® is a glucosamine salt of methyltetrahydrofolate (MTHF). In a pivotal study, it was shown to be around twice as bioavailable as folic acid, because its use resulted in much lower levels of unmetabolised folic acid than other forms. Other research has shown that Quatrefolic® has around 10% higher bioavailability when compared to other alternative folate forms like calcium salt forms of MTHF, reinforcing its position as a superior folate source for daily wellness supplements for immunity and long- term health support.
IT MATTERS WITH AGE!
The importance of women’s folate requirements is usually associated with fertility and birth, but women need ample vitamin B well beyond their childbearing years. Because it supports heart, cognitive and immune health, folate can be counted as one of the most essential vitamins for women over 50. An active, highly bioavailable form of folate, like Quatrefolic® is especially relevant in the formulation of vitamins for over 50 female health optimisation. In a women’s multivitamin over 50 formulation, efficiency and tolerability matter. Men also benefit from maintaining optimal folate status and the roles it plays in energy metabolism and DNA repair. Quality multivitamins for men will carefully consider the form of folate used, in the understanding that bioavailable folate is a significant contributor to the benefits of men’s multis. Choosing a men’s multivitamin that includes Quatrefolic® in the formulation ensures optimal absorption and utilisation of this nutrient.
WHOLEFOOD PHILOSOPHY MEETS ADVANCE SCIENCE
Quatrefolic® is a perfect fit for both men and women’s multivitamins with wholefoods. Quatrefolic® supports the body at the cellular level, making it an ideal choice for people of all ages.
THE BOTTOM LINE
Quatrefolic® is a significantly advanced form of folic acid, surpassing the bioavailability of folic acid and MTHF forms and can make a real difference in the quality, efficacy and long-term health outcomes of your daily multivitamin regime.
